Common Uses: This medicine is a biguanide-type medicine used along with a diet and exercise program to control high blood sugar in patients with type 2 diabetes. This medicine works by helping restore your body's proper response to the insulin you naturally produce, and by decreasing the amount of sugar that your liver makes and that your stomach/intestines absorb. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, circulation problems, and sexual function problems.

Generic Name: E: METFORMIN (met-FOR-min)

[Metformin]. Medications should only be taken in accordance with the advice of your medical professional.

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How to use this Medicine: Follow the directions for using this medicine provided by your doctor. TAKE THIS MEDICINE with food. DRINK PLENTY OF FLUIDS while taking this medicine. CONTINUE TO TAKE THIS MEDICINE even if you feel well. Do not miss any doses. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day. This medicine may come with a patient information leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. STORE THE U.S. PRODUCT at room temperature between 68 and 77 degrees F (20 and 25 degrees C), away from light and moisture. Brief storage from 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. STORE THE CANADIAN PRODUCT between 59 and 86 degrees F (15 and 30 degrees C). Keep all medicines away from children and pets. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. DO NOT take 2 doses at once.

Cautions: DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. FOLLOW THE DIETARY PLAN provided by your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. Laboratory and/or medical tests such as liver and kidney function tests, fasting blood glucose, glycosylated hemoglobin, or complete blood counts, should be done to monitor your progress or to check for side effects. Regularly check your blood or urine sugar as directed by your doctor. If your blood sugars have been under control and suddenly are difficult to manage, contact your doctor as soon as possible. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, LABORATORY TESTS, OR SURGERY, tell the doctor or dentist that you are using this medicine. During times of stress such as fever, infection, injury, or surgery it may be more difficult to control your blood sugar. Consult your doctor, as a change in your medicine may be required. This medicine usually does not cause low blood sugar, or hypoglycemia, but this effect may occur if you do not consume enough calories from food, juices, fruit, or other sources. The symptoms of hypoglycemia include chills, cold sweat, dizziness, drowsiness, shaking, rapid heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you are in a situation where you don't have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level. Tell your doctor immediately about the reaction. To help prevent hypoglycemia, eat meals on a regular schedule and do not skip meals. Symptoms of high blood sugar, or hyperglycemia, include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor. If these symptoms occur, tell your doctor immediately. Your medicine dosage may need to be increased. LIMIT ALCOHOL INTAKE while using this medicine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. Caution is advised when using this medicine in the elderly since they may be more sensitive to the effects of this medicine. FOR WOMEN: This medicine can cause changes in the menstrual cycle of women with certain fertility problems, therefore increasing the risk of becoming pregnant. Consult your doctor or pharmacist about the use of reliable birth control while using this medicine. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking this medicine.

Possible Side Effects: SIDE EFFECTS, that may go away during treatment, include metallic taste in mouth, nausea, stomach upset, flatulence, and diarrhea. If they continue or are bothersome, check with your doctor. If stomach symptoms recur after you are on the same dose for several days or weeks, tell your doctor immediately. A late recurrence of stomach symptoms may be due to a serious medical condition called lactic acidosis. CONTACT YOUR DOCTOR IMMEDIATELY if you experience unusual tiredness, severe drowsiness, cold skin, muscle pain or aches, rapid breathing, or unusually slow or irregular heartbeat. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

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[Metformin]

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(Reuters Health) - Children's visits to the emergency room for serious food-allergy reactions may be on the rise, if the experience of one major U.S. medical center is an indicator. Researchers at Children's Hospital Boston found that the number of food-induced allergic reactions treated in their ER more than doubled over six years -- from 164 cases in 2001, to 391 in 2006. There was an even sharper increase in the number of more serious, and sometimes life-threatening, reactions known as anaphylaxis. Signs and symptoms of anaphylaxis include skin reactions like hives and flushed or pale skin; nausea, vomiting or diarrhea; dizziness or fainting; difficulty breathing; and a sudden drop in blood pressure that can lead to shock. In 2001, the current study found, there were 78 cases of food-induced anaphylaxis; in 2006, that number was 207. That corresponded to a rate of 15 anaphylaxis cases for every 10,000 ER visits in 2001, and a rate of 38 per 10,000 in 2006, the researchers report in the Journal of Allergy and Clinical Immunology. The reasons for the increases cannot be gleaned from the data. But the findings are in line with studies pointing to a general increase in food allergies among U.S. children in recent years, first author Dr. Susan A. Rudders told Reuters Health in an email. According to the U.S. Centers for Disease Control and Prevention, 3 million school-aged children in the U.S. had a food allergy in 2007, which was up 18 percent from 10 years earlier.

Any person who suspects they are suffering from a medical condition, problem, disorder should prompty seek the assistance of a professional and qualified health care provider.